LRRC19 antibody (C-Term)

Catalog No. ABIN500196

The Rabbit Polyclonal anti-LRRC19 antibody (ABIN500196) specifically detects LRRC19 in WB, IF and EIA. The antibody is reactive with Human and Mouse samples.

Quick Overview for LRRC19 antibody (C-Term) (ABIN500196)

Target: LRRC19 (Leucine Rich Repeat Containing 19 (LRRC19))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC19 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-LRRC19 Antibody

Binding Specificity: C-Term

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Peptide affinity chromatography

Immunogen: LRRC19 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human LRRC19.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for LRRC19

Target: LRRC19 (Leucine Rich Repeat Containing 19 (LRRC19))

Alternative Name: LRRC19

Background: LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kB and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.Synonyms: Leucine-rich repeat-containing protein 19

Gene ID: 64922

NCBI Accession: NP_075052

UniProt: Q9H756