Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

MOAP1 antibody (Center)

MOAP1 Reactivity: Human, Mouse WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500228
  • Target See all MOAP1 Antibodies
    MOAP1 (Modulator of Apoptosis 1 (MOAP1))
    Binding Specificity
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 25
    • 4
    • 2
    Human, Mouse
    Host
    • 22
    • 5
    Rabbit
    Clonality
    • 24
    • 3
    Polyclonal
    Conjugate
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    This MOAP1 antibody is un-conjugated
    Application
    • 25
    • 16
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects Modulator of apoptosis 1 at enter.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse
    Purification
    Peptide affinity chromatography
    Immunogen
    MAP-1 antibody was raised against a 15 amino acid peptide from near the center of human MAP-1.
    Isotype
    IgG
    Top Product
    Discover our top product MOAP1 Primary Antibody
  • Application Notes
    ELISA. Western blot: 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    MOAP1 (Modulator of Apoptosis 1 (MOAP1))
    Alternative Name
    MOAP1 (MOAP1 Products)
    Synonyms
    MOAP1 antibody, MAP-1 antibody, PNMA4 antibody, AA987038 antibody, Map-1 antibody, Pnma4 antibody, modulator of apoptosis 1 antibody, modulator of apoptosis 1 S homeolog antibody, MOAP1 antibody, moap1.S antibody, Moap1 antibody
    Background
    Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). Members of the Bcl-2 family are known to be critical regulators of this process. These proteins are characterized by the presence of several conserved motifs termed Bcl-2 homology (BH) domains (reviewed in 2 and 3). A related protein termed MAP-1 has recently been identified. This protein contains a BH3-like domain and induces caspase-dependent apoptosis in mammalian cells when overexpressed. It forms homodimers and associates with Bcl-2 family members such as Bax, Bcl-2, and Bcl-XL in vitro and in vivo (4). It has been suggested that MAP-1 associates with the tumor suppressor RASSF1A following death receptor activation, allowing a conformational change in Bax that leads to cellular apoptosis (5).Synonyms: MAP-1, MAP1, Modulator of apoptosis 1
    Gene ID
    64112
    NCBI Accession
    NP_071434
    UniProt
    Q96BY2
    Pathways
    Positive Regulation of Endopeptidase Activity
You are here:
Support