FAM134B antibody (AA 210-310) (AbBy Fluor® 680)

Catalog No. ABIN5002361

The AbBy Fluor® 680-conjugated Rabbit Polyclonal anti-FAM134B antibody (ABIN5002361) specifically detects FAM134B in WB, FACS, IF (cc) and IF (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for FAM134B antibody (AA 210-310) (AbBy Fluor® 680) (ABIN5002361)

Target: FAM134B (Family with Sequence Similarity 134, Member B (FAM134B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM134B antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-FAM134B Antibody (AbBy Fluor® 680)

Binding Specificity: AA 210-310

Specificity: There is a chance that this protein will cross-react with MSL2 based on a 73 % non-sequential sequence similarity.

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAM134B

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FAM134B

Target: FAM134B (Family with Sequence Similarity 134, Member B (FAM134B))

Alternative Name: FAM134B

Background:

Synonyms: JK1, JK-1, Reticulophagy receptor FAM134B, FAM134B

Background: Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes (PubMed:26040720). Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins (PubMed:26040720). Required for long-term survival of nociceptive and autonomic ganglion neurons (PubMed:19838196, PubMed:26040720).

Gene ID: 54463

UniProt: Q9H6L5