FANCG antibody (pSer383) (AbBy Fluor® 680)

Catalog No. ABIN5002457

This anti-FANCG antibody is a Rabbit Polyclonal antibody detecting FANCG in WB, IF (cc) and IF (p). Suitable for Human.

Quick Overview for FANCG antibody (pSer383) (AbBy Fluor® 680) (ABIN5002457)

Target: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCG antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-FANCG Antibody (AbBy Fluor® 680)

Binding Specificity: pSer383

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human FANCG around the phosphorylation site of Ser383

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FANCG

Target: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Alternative Name: FANCG

Background:

Synonyms: FANCG phospho S383, p-FANCG phospho S383, DNA repair protein XRCC9, DNA-repair protein XRCC9, FAG, Fanconi anaemia complementation group G, Protein FACG, X ray repair, complementing defective, in Chinese hamster cells 9, XRCC9.

Background: FANCG, involved in Fanconi anemia, confers resistance to both hygromycin and mitomycin C. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies. A minimum of 8 FA genes have been identified.

Gene ID: 2189

Pathways: DNA Damage Repair