METTL7A antibody (C-Term)

Catalog No. ABIN500272

This Rabbit Polyclonal antibody specifically detects METTL7A in WB and EIA. It exhibits reactivity toward Human and Mouse.

Quick Overview for METTL7A antibody (C-Term) (ABIN500272)

Target: METTL7A (Methyltransferase Like 7A (METTL7A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This METTL7A antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-METTL7A Antibody

Binding Specificity: C-Term

Specificity: This antibody detects METTL7A C-term. It is predicted to not cross-react with MettL7B.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Peptide affinity chromatography

Immunogen: MettL7A antibody was raised against a 12 amino acid peptide near the carboxy terminus of human MettL7A.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for METTL7A

Target: METTL7A (Methyltransferase Like 7A (METTL7A))

Alternative Name: METTL7A

Background: MettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis. At least two isoforms of MettL7A are known to exist.Synonyms: Methyltransferase-like protein 7A, PRO0066, UNQ1902/PRO4348

Gene ID: 25840

NCBI Accession: NP_054752

UniProt: Q9H8H3