METTL7B antibody (N-Term)

Catalog No. ABIN500278

This Rabbit Polyclonal antibody specifically detects METTL7B in WB, IHC (p) and EIA. It exhibits reactivity toward Human and Mouse.

Quick Overview for METTL7B antibody (N-Term) (ABIN500278)

Target: METTL7B (Methyltransferase Like 7B (METTL7B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This METTL7B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-METTL7B Antibody

Binding Specificity: N-Term

Specificity: This antibody detects METTL7B at N-term.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Peptide affinity chromatography

Immunogen: MettL7B antibody was raised against a 13 amino acid peptide near the amino terminus of human MettL7B.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 2 - 4 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for METTL7B

Target: METTL7B (Methyltransferase Like 7B (METTL7B))

Alternative Name: METTL7B

Background: MettL7b belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis. This MettL7B antibody is predicted to not cross-react with MettL7A.Synonyms: Methyltransferase-like protein 7B, UNQ594/PRO1180

Gene ID: 196410

NCBI Accession: NP_689850

UniProt: Q6UX53