Neudesin antibody (C-Term)

Catalog No. ABIN500328

Product Details anti-Neudesin Antibody

Target: Neudesin (NENF)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neudesin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects Neudesin.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogen: NENF antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human NENF.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for Neudesin

Target: Neudesin (NENF)

Alternative Name: Neudesin (NENF Products)

Synonyms: nenf antibody, CIR2 antibody, SCIRP10 antibody, SPUF antibody, Spuf antibody, 1110060M21Rik antibody, neudesin neurotrophic factor antibody, neuron derived neurotrophic factor antibody, nenf antibody, NENF antibody, Nenf antibody

Background: NENF is a secreted protein that is expressed in neurons but not glial cells of the brain. This protein has neurotrophic activity in primary cultured mouse neurons but not mitogenic activity in primary cultured mouse astrocytes. NENF activated mitogen-activated protein (MAP) and phosphotidylinositol-3 kinase pathways and could be inhibited by pertussis toxin but not receptor tyrosine kinases, suggesting that NENF acts through a Gi/Go-protein-coupled receptor. Despite its predicted molecular weight of ~20 kDa, NENF is observed at 37 kDa in SDS-PAGE.Synonyms: CIR2, Cell immortalization-related protein 2, NENF, Neuron-derived neurotrophic factor, SPUF, Secreted protein of unknown function

Gene ID: 29937

NCBI Accession: NP_037481

UniProt: Q9UMX5