GCN2 antibody (pThr899) (AbBy Fluor® 750)

Catalog No. ABIN5003296

The Rabbit Polyclonal anti-GCN2 antibody is suitable to detect GCN2 in samples from Human. It has been validated for WB and FACS.

Quick Overview for GCN2 antibody (pThr899) (AbBy Fluor® 750) (ABIN5003296)

Target: GCN2 (EIF2AK4) (Eukaryotic Translation Initiation Factor 2 alpha Kinase 4 (EIF2AK4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCN2 antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-GCN2 Antibody (AbBy Fluor® 750)

Binding Specificity: pThr899

Purpose: Phospho-GCN2 (Thr899) Polyclonal Antibody, AbBy Fluor-750 Conjugated

Specificity: This phosphorylation site is homologous to Thr898 in Mouse and Thr899 in Rat.

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human GCN2 around the phosphorylation site of Thr899

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), FCM(1:20-100)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GCN2

Target: GCN2 (EIF2AK4) (Eukaryotic Translation Initiation Factor 2 alpha Kinase 4 (EIF2AK4))

Alternative Name: GCN2

Background:

Synonyms: GCN2, PVOD2, Eukaryotic translation initiation factor 2-alpha kinase 4, GCN2-like protein, EIF2AK4, KIAA1338

Background: GCN2 belongs to a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor 2 to downregulate protein synthesis in response to varied cellular stresses.

Gene ID: 440275

UniProt: Q9P2K8

Pathways: ER-Nucleus Signaling, Hepatitis C