Granzyme D/B/E/N/G/F/H antibody (AbBy Fluor® 680)
Quick Overview for Granzyme D/B/E/N/G/F/H antibody (AbBy Fluor® 680) (ABIN5004034)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Pig,Horse
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human Granzyme D/B/E/N/G/F/H
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Isotype
- IgG
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Application Notes
- IF(IHC-P) 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Expiry Date
- 12 months
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- Granzyme D/B/E/N/G/F/H
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Alternative Name
- Granzyme D/ B/ E/ N/ G/ F/ H
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Background
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Synonyms: Granzyme D, Granzyme B, Granzyme E, Granzyme N, Granzyme G, Granzyme F, Granzyme H, Cathepsin G-like 2, CCP-X, CCP3, CCP4, CCP5, CGL-2, CSP-C, Ctla-5, Ctla-6, Ctla-7, CTLA1, CTSGL2, Grz d, Grz e, Grz f, Grz g, GZMD, Gzme, Gzmf, Gzmg, GZMH, MCSP-2, MCSP-3, MGC117682, Rnkp7, mast cell proteinase-3-like, Cytotoxic T-lymphocyte proteinase, Granzyme H precursor, Cytotoxic serine protease-C, CSP-C.
Background: protease required for lymphocyte cytotoxic granules to lyse target cells [RGD]. Granzyme B is a cysteine protease found in the cytoplasmic lysosome-like granules of cytolytic T lymphocytes (CTL) and natural killer (NK) cells and is is required for the induction of target cell lysis. This occurs as part of cell mediated immune responses, and can activate apoptosis in target cells by both caspase dependent and caspase independent mechanisms.
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Gene ID
- 2999
Target
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