LAMA3 antibody (AA 2700-2750) (AbBy Fluor® 680)

Catalog No. ABIN5006023

Product Details anti-LAMA3 Antibody (AbBy Fluor® 680)

Target: LAMA3 (Laminin, alpha 3 (LAMA3))

Binding Specificity: AA 2700-2750

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAMA3 antibody is conjugated to AbBy Fluor® 680

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LAMA3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Storage: 4 °C

Storage Comment: Store at 4°C

Expiry Date: 12 months

Target Details for LAMA3

Target: LAMA3 (Laminin, alpha 3 (LAMA3))

Alternative Name: LAMA3/ Laminin 5 alpha 3 (LAMA3 Products)

Background:

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80, (3) differentiation of keratinocytes.

Subcellular location: Extracellular, Secreted

Synonyms: E170, LOCS, BM600, LAMNA, Laminin subunit alpha-3, Epiligrin 170 kDa subunit, Epiligrin subunit alpha, Kalinin subunit alpha, Laminin-5 subunit alpha, Laminin-6 subunit alpha, Laminin-7 subunit alpha, Nicein subunit alpha, LAMA3

Gene ID: 3909

UniProt: Q16787