RPAIN antibody (C-Term)

Catalog No. ABIN500632

This Rabbit Polyclonal antibody specifically detects RPAIN in WB, EIA and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for RPAIN antibody (C-Term) (ABIN500632)

Target: RPAIN (RPA Interacting Protein (RPAIN))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPAIN antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RPAIN Antibody

Binding Specificity: C-Term

Specificity: This antibody detects RPA Interacting Protein at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogen: RPA IP antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human RPA IP.

Isotype: IgG

Application Details

Application Notes: ELISA. Wester blot. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for RPAIN

Target: RPAIN (RPA Interacting Protein (RPAIN))

Alternative Name: RPAIN / RIP

Background: Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair and recombination. RPA interacting protein (RPA IP) has been identified as an adapter protein that is involved in RPA nuclear import instead of the prototypical importin proteins that normally mediate nuclear import. Multiple isoforms of RPA IP are known to exist, with the longest isoform localized to the cytoplasm. Isoform 2 is sumoylated and is located in the PML nuclear body within the nucleus. It has been suggested that this isoform mediates the localization of the RPA complex into the PML nuclear body, thereby participating in RPA function in DNA metabolism.Synonyms: RPA-interacting protein

Gene ID: 84268

NCBI Accession: NP_001028174

UniProt: Q86UA6

Pathways: Protein targeting to Nucleus