MAPK11 antibody (AA 21-120) (AbBy Fluor® 750)

Catalog No. ABIN5006525

This anti-MAPK11 antibody is a Rabbit Polyclonal antibody detecting MAPK11 in WB, IF (cc) and IF (p). Suitable for Rat.

Quick Overview for MAPK11 antibody (AA 21-120) (AbBy Fluor® 750) (ABIN5006525)

Target: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPK11 antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-MAPK11 Antibody (AbBy Fluor® 750)

Binding Specificity: AA 21-120

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MAPK11

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MAPK11

Target: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Alternative Name: MAPK11

Background:

Synonyms: P38B, SAPK2, p38-2, PRKM11, SAPK2B, p38Beta, P38BETA2, Mitogen-activated protein kinase 11, MAP kinase 11, MAPK 11, Mitogen-activated protein kinase p38 beta, MAP kinase p38 beta, Stress-activated protein kinase 2b, MAPK11

Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. MAPK11 is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.

Gene ID: 5600

UniProt: Q15759

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Response to Water Deprivation, Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Hepatitis C, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins