DLGAP4 antibody (Center)
Quick Overview for DLGAP4 antibody (Center) (ABIN500658)
Target
See all DLGAP4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Center
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Specificity
- This antibody detects SAPAP4. It will not cross-react with other SAPAP proteins.
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Cross-Reactivity (Details)
- Species reactivity (tested):Human
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Purification
- Peptide affinity chromatography
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Immunogen
- SAPAP4 antibody was raised against a 13 amino acid peptide from near the center of human SAPAP4.
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Isotype
- IgG
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Application Notes
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ELISA. Western blot: 0.5 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- DLGAP4 (Discs, Large (Drosophila) Homolog-Associated Protein 4 (DLGAP4))
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Alternative Name
- DLGAP4 / SAPAP4
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Background
- SAP90/PSD-95-associated protein 4 (SAPAP4, also known as DLGAP4) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP4 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP4 mRNA is targeted to cell bodies in a similar manner to SAPAP1 and -2, whereas SAPAP3 mRNA is detected mainly in cell bodies. At least three isoforms of SAPAP2 are known to exist.Synonyms: DAP-4, DAP4, Disks large-associated protein 4, KIAA0964, PSD-95/SAP90-binding protein 4, SAP90/PSD-95-associated protein 4
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Gene ID
- 22839
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NCBI Accession
- NP_055717
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UniProt
- Q9Y2H0
Target
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