MCC antibody (AA 901-1019) (AbBy Fluor® 680)

Catalog No. ABIN5006621

The AbBy Fluor® 680-conjugated Rabbit Polyclonal anti-MCC antibody (ABIN5006621) specifically detects MCC in WB, IF (cc) and IF (p). The antibody is reactive with Human samples.

Quick Overview for MCC antibody (AA 901-1019) (AbBy Fluor® 680) (ABIN5006621)

Target: MCC (Mutated in Colorectal Cancers (MCC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCC antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-MCC Antibody (AbBy Fluor® 680)

Binding Specificity: AA 901-1019

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MCC

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MCC

Target: MCC (Mutated in Colorectal Cancers (MCC))

Alternative Name: MCC

Background:

Synonyms: Colorectal mutant cancer protein, MCC 1, MCC-1, MCC1, Mutated in colorectal cancers, Protein MCC, CRCM_HUMAN.

Background: This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Gene ID: 4163

UniProt: P23508