SLITRK6 antibody (Center)

Catalog No. ABIN500772

This anti-SLITRK6 antibody is a Rabbit Polyclonal antibody detecting SLITRK6 in WB, IHC (p) and EIA. Suitable for Human, Mouse and Rat.

Quick Overview for SLITRK6 antibody (Center) (ABIN500772)

Target: SLITRK6 (SLIT and NTRK-Like Family, Member 6 (SLITRK6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLITRK6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-SLITRK6 Antibody

Binding Specificity: Center

Specificity: This antibody detects SLITRK6 at center. It is predicted to have no cross-reactivity to other Slitrk proteins.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogen: Slitrk6 antibody was raised against a 13 amino acid peptide from near the center of human Slitrk6.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for SLITRK6

Target: SLITRK6 (SLIT and NTRK-Like Family, Member 6 (SLITRK6))

Alternative Name: SLITRK6

Background: SLIT and NTRK-like family 6 (Slitrk6) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family (1,2). Slitrk6 expression has been observed in tissues such as tongue, lung, gastrointestinal tract, and pancreas. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk6 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth. At least two isoforms of Slitrk6 are known to exisit.Synonyms: SLIT and NTRK-like protein 6

Gene ID: 84189

UniProt: Q9H5Y7