CDK5R1 antibody (pSer113) (AbBy Fluor® 750)

Catalog No. ABIN5008133

The AbBy Fluor® 750-conjugated Rabbit Polyclonal anti-CDK5R1 antibody (ABIN5008133) specifically detects CDK5R1 in WB, IF (cc) and IF (p). The antibody is reactive with Mouse samples.

Quick Overview for CDK5R1 antibody (pSer113) (AbBy Fluor® 750) (ABIN5008133)

Target: CDK5R1 (Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK5R1 antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CDK5R1 Antibody (AbBy Fluor® 750)

Binding Specificity: pSer113

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Telomerase Binding Protein_P23 around the phosphorylation site of Ser113

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CDK5R1

Target: CDK5R1 (Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))

Alternative Name: p23

Background:

Synonyms: Telomerase Binding Protein_P23, Prostaglandin E synthase 3, Cytosolic prostaglandin E2 synthase, cPGES, Telomerase-binding protein p23, Hsp90 co-chaperone, Progesterone receptor complex p23, PTGES3, P23, TEBP, TEBP_HUMAN.

Background: Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Belongs to the p23/wos2 family.

Gene ID: 10728

Pathways: Stem Cell Maintenance, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity