PLIN3 antibody (C-Term)

Catalog No. ABIN500921

The Rabbit Polyclonal anti-PLIN3 antibody is suitable to detect PLIN3 in samples from Human and Rat. It has been validated for WB, IHC (p), IF and EIA.

Quick Overview for PLIN3 antibody (C-Term) (ABIN500921)

Target: PLIN3 (Perilipin 3 (PLIN3))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLIN3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-PLIN3 Antibody

Binding Specificity: C-Term

Specificity: This antibody detects TIP47 / M6PRBP1 at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human, Rat

Purification: Peptide Affinity Chromatography

Immunogen: TIP47 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of Human TIP47.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PLIN3

Target: PLIN3 (Perilipin 3 (PLIN3))

Alternative Name: TIP47 / M6PRBP1

Background: Tail-interacting protein (TIP47) is a cytosolic protein essential for the transport of mannose-6-phosphate receptors (MPRs) from endosomes to the trans-Golgi compartments in cells. TIP47 is recruited from the cytoplasm to the late endosomal surface by the Ras-associated protein Rab9 GTPase, enabling it to bind more efficiently to MPR cytoplasmic domains. Recently, it was shown that TIP47 regulates the expression of Rab9, as expression of siRNA to TIP47 in transfected cells dramatically decreased the half-life of the Rab9 protein in addition to stabilizing the subcellular localization of Rab9. At least two isoforms of TIP47 are known to exist.Synonyms: 47 kDa mannose 6-phosphate receptor-binding protein, Cargo selection protein TIP47, Mannose-6-phosphate receptor-binding protein 1, Placental protein 17

Gene ID: 10226

UniProt: O60664