TCTN1 antibody (AA 481-587) (AbBy Fluor® 680)

Catalog No. ABIN5011456

The Rabbit Polyclonal anti-TCTN1 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect TCTN1 in samples from Rat.

Quick Overview for TCTN1 antibody (AA 481-587) (AbBy Fluor® 680) (ABIN5011456)

Target: TCTN1 (Tectonic Family Member 1 (TCTN1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCTN1 antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-TCTN1 Antibody (AbBy Fluor® 680)

Binding Specificity: AA 481-587

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TCTN1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TCTN1

Target: TCTN1 (Tectonic Family Member 1 (TCTN1))

Alternative Name: TCTN1

Background:

Synonyms: TCTN1, TECT1_HUMAN, Tectonic-1.

Background: Regulator of Hedgehog (Hh), required for both activation and inhibition of the Hh pathway in the patterning of the neural tube. During neural tube development, it is required for formation of the most ventral cell types and for full Hh pathway activation. Functions in Hh signal transduction to fully activate the pathway in the presence of high Hh levels and to repress the pathway in the absence of Hh signals. Modulates Hh signal transduction downstream of SMO and RAB23.

Pathways: Tube Formation