Tumor Protein p73 antibody (AA 501-631) (AbBy Fluor® 680)

Catalog No. ABIN5011821

This Rabbit Polyclonal antibody specifically detects Tumor Protein p73 in IF (p) and IF (cc). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Tumor Protein p73 antibody (AA 501-631) (AbBy Fluor® 680) (ABIN5011821)

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tumor Protein p73 antibody is conjugated to AbBy Fluor® 680

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-Tumor Protein p73 Antibody (AbBy Fluor® 680)

Binding Specificity: AA 501-631

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Tp73 protein

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Tumor Protein p73

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Alternative Name: Tp73 protein

Background:

Synonyms: p73, Tp73, TAp73, Tumor protein p73, p53-like transcription factor, p53-related protein, Trp73

Background: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.

Gene ID: 22062

UniProt: Q9JJP2

Pathways: Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus