Tryptophan Hydroxylase 1 antibody (AA 31-150) (AbBy Fluor® 750)

Catalog No. ABIN5012009

This anti-Tryptophan Hydroxylase 1 antibody is a Rabbit Polyclonal antibody detecting Tryptophan Hydroxylase 1 in WB, IF (cc) and IF (p). Suitable for Human, Mouse and Rat.

Quick Overview for Tryptophan Hydroxylase 1 antibody (AA 31-150) (AbBy Fluor® 750) (ABIN5012009)

Target: Tryptophan Hydroxylase 1 (TPH1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tryptophan Hydroxylase 1 antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Tryptophan Hydroxylase 1 Antibody (AbBy Fluor® 750)

Binding Specificity: AA 31-150

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Tryptophan 5-hydroxylase 1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Tryptophan Hydroxylase 1

Target: Tryptophan Hydroxylase 1 (TPH1)

Alternative Name: Tryptophan 5-hydroxylase 1, Tryptophan 5-hydroxylase 2

Background:

Synonyms: TPRH, TRPH, Tryptophan 5-hydroxylase 1, Tryptophan 5-monooxygenase 1, TPH1, TPH

Background: This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.[provided by RefSeq, Apr 2009].

Gene ID: 7166

UniProt: P17752

Pathways: Feeding Behaviour