ZIC2 antibody (AA 201-300) (AbBy Fluor® 680)

Catalog No. ABIN5012682

This Rabbit Polyclonal antibody specifically detects ZIC2 in WB, IF (cc) and IF (p). It exhibits reactivity toward Rat.

Quick Overview for ZIC2 antibody (AA 201-300) (AbBy Fluor® 680) (ABIN5012682)

Target: ZIC2

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZIC2 antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ZIC2 Antibody (AbBy Fluor® 680)

Binding Specificity: AA 201-300

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Sheep,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Zic2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ZIC2

Target: ZIC2

Alternative Name: Zic2

Background:

Synonyms: HPE 5, HPE5, Odd paired homolog Drosophila, Zic 2, Zic family member 2 odd paired Drosophila homolog, Zic family member 2, ZIC2, ZIC2_HUMAN, Zinc finger protein of the cerebellum 2, Zinc finger protein ZIC 2, Zinc finger protein Zic2.

Background: Zic2 is a C2H2 zinc finger transcription factor that influences forebrain development. Zic2 is a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Zic2 transcript is abundant in the dorsal neural tube/spinal cord, and in the hindbrain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.

Pathways: Tube Formation