DKC1 antibody (AA 298-509)

Catalog No. ABIN5013473

This Rabbit Polyclonal antibody specifically detects DKC1 in WB, IHC, IP and ICC. It exhibits reactivity toward Rat.

Quick Overview for DKC1 antibody (AA 298-509) (ABIN5013473)

Target: DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DKC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details anti-DKC1 Antibody

Binding Specificity: AA 298-509

Purpose: Polyclonal Antibody to Dyskerin (DKC)

Specificity: The antibody is a rabbit polyclonal antibody raised against DKC. It has been selected for its ability to recognize DKC in immunohistochemical staining and western blotting.

Cross-Reactivity: Human

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: RPC446Ra01Recombinant Dyskerin (DKC)

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.2-2 μg/mL,1:250-2500 Immunohistochemistry: 5-20 μg/mL,1:25-100 Immunocytochemistry: 5-20 μg/mL,1:25-100 Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 500 μg/mL

Buffer: PBS, pH 7.4, containing 0.01 % SKL, 1 mM DTT, 5 % Trehalose and Proclin300.

Preservative: Dithiothreitol (DTT), ProClin

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Target Details for DKC1

Target: DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))

Alternative Name: Dyskerin

Background: DKC1, NAP57, NOLA4, NAP57, Dyskeratosis Congenita 1, H/ACA Ribonucleoprotein Complex Subunit 4, Nopp140-associated protein of 57 kDa, Nucleolar protein family A member 4

Pathways: Telomere Maintenance