DKC1 antibody (AA 298-509)

Catalog No. ABIN5013474

Product Details anti-DKC1 Antibody

Target: DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))

Binding Specificity: AA 298-509

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DKC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Purpose: Polyclonal Antibody to Dyskerin (DKC)

Specificity: The antibody is a rabbit polyclonal antibody raised against DKC. It has been selected for its ability to recognize DKC in immunohistochemical staining and western blotting.

Cross-Reactivity: Human

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: RPC446Mu01Recombinant Dyskerin (DKC)

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.5-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 500 μg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Preservative: Sodium azide

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Target Details for DKC1

Target: DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))

Alternative Name: Dyskerin (DKC1 Products)

Background: DKC1, NAP57, NOLA4, NAP57, Dyskeratosis Congenita 1, H/ACA Ribonucleoprotein Complex Subunit 4, Nopp140-associated protein of 57 kDa, Nucleolar protein family A member 4

Pathways: Telomere Maintenance