Liver Arginase antibody (AA 11-230)

Catalog No. ABIN5027039

This anti-Liver Arginase antibody is a Mouse Monoclonal antibody detecting Liver Arginase in WB and IHC. Suitable for Human.

Quick Overview for Liver Arginase antibody (AA 11-230) (ABIN5027039)

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Liver Arginase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: ABM4B35

Product Details anti-Liver Arginase Antibody

Binding Specificity: AA 11-230

Purification: Protein G Chromatography

Immunogen: A partial length recombinant Arginase-1 protein (amino acids 11-230) was used as the immunogen for this antibody

Isotype: IgG2b kappa

Application Details

Application Notes: WB: 2-4 μg/mL, IHC: 5-15 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for Liver Arginase

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Alternative Name: Arginase-1

Background: Arginase-1 (Arg-1) is a binuclear manganese metalloenzyme that catalyzes the hydrolysis of arginine to ornithine and urea. It is expressed in normal human liver with a high degree of specificity, concentrated in periportal hepatocytes. Arginase-1 are urea cycle enzymes used to distinguish hepatocellular carcinoma from other carcinomas. Two transcript variants encoding different isoforms have been found for this gene. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.

Molecular Weight: 35 kDa

Gene ID: 383

UniProt: P05089

Pathways: Cellular Response to Molecule of Bacterial Origin