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CD73 antibody (AA 145-346)

The Mouse Monoclonal anti-CD73 antibody is suitable to detect CD73 in samples from Human. It has been validated for WB and IHC.

IHC

1 image

Catalog No. ABIN5027098

$406.15

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Quick Overview for CD73 antibody (AA 145-346) (ABIN5027098)

Target

See all CD73 (NT5E) Antibodies

CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))

Reactivity

Human

Host

Mouse

Clonality

Monoclonal

Conjugate

This CD73 antibody is un-conjugated

Application

Western Blotting (WB), Immunohistochemistry (IHC)

Clone

ABM40E2

Discover our top product NT5E Primary Antibody

Binding Specificity
18

16

9

9

6

6

6

5

4

4

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 145-346

Purification

Protein G Chromatography

Immunogen

A partial length recombinant CD73 protein (amino acids 145-346) was used as the immunogen for this antibody.

Isotype

IgG2a kappa
anti-5'-Nucleotidase, Ecto (CD73) (NT5E) (AA 30-250) antibody
NT5E Reactivity: Human WB, IHC, ELISA Host: Mouse Monoclonal 4G6B10 unconjugated

anti-5'-Nucleotidase, Ecto (CD73) (NT5E) (AA 520-550), (C-Term) antibody
NT5E Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB02846 unconjugated

anti-5'-Nucleotidase, Ecto (CD73) (NT5E) (AA 29-500) antibody
NT5E Reactivity: Human WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated

anti-5'-Nucleotidase, Ecto (CD73) (NT5E) antibody
NT5E Reactivity: Human WB, IHC, FACS, IF, ELISA Host: Mouse Monoclonal NT5E-2545 unconjugated

anti-5'-Nucleotidase, Ecto (CD73) (NT5E) antibody
NT5E Reactivity: Human WB, IHC, FACS, IF Host: Mouse Monoclonal NT5E-2503 unconjugated

anti-5'-Nucleotidase, Ecto (CD73) (NT5E) (AA 290-550) antibody
NT5E Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated

anti-5'-Nucleotidase, Ecto (CD73) (NT5E) (AA 30-250) antibody
NT5E Reactivity: Human WB, IHC, FACS, ELISA Host: Mouse Monoclonal 4G6E3 unconjugated

anti-5'-Nucleotidase, Ecto (CD73) (NT5E) (AA 48-527) antibody
NT5E Reactivity: Cow WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated

anti-5'-Nucleotidase, Ecto (CD73) (NT5E) antibody (PE)
NT5E Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal AD2 PE

anti-5'-Nucleotidase, Ecto (CD73) (NT5E) (AA 151-250) antibody
NT5E Reactivity: Human, Mouse, Rat, Cow, Dog, Sheep WB, FACS, ELISA, ICC, IHC (p), IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated

Application Notes

WB: 2-4 μg/mL, IHC: 5 μg/mL

Restrictions

For Research Use only
Concentration

0.5 mg/mL

Buffer

PBS containing 0.05 % BSA, PH 7.4

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C/-20 °C

Storage Comment

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Target

CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))

Alternative Name

CD73

Background

CD73, also known as ecto-5'-nucleotidase, is a glycosyl-phosphatidylinositol linked plasma membrane glycoprotein that is expressed on multiple cell types and in different tissues. It is a key enzyme in the regulation of purinergic signaling and inflammatory reactions. It hydrolyzes extracellular AMP into adenosine, which dampens immune cell activation, and reduces leukocyte trafficking CD73 potently suppresses antitumor T cell responses through its ability to generate adenosine. It has also emerged as an important regulator of tissue homeostasis and pathophysiologic responses related to immunity, inflammation, pain, ischemia, tissue fibrosis and cancer.

Molecular Weight

63 kDa

Gene ID

4907

UniProt

P21589

Pathways

Synaptic Membrane, Ribonucleoside Biosynthetic Process