CUEDC2 antibody (AA 100-280)

Catalog No. ABIN5027122

The Rabbit Polyclonal anti-CUEDC2 antibody is suitable to detect CUEDC2 in samples from Human. It has been validated for WB.

Quick Overview for CUEDC2 antibody (AA 100-280) (ABIN5027122)

Target: CUEDC2 (CUE Domain Containing 2 (CUEDC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CUEDC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CUEDC2 Antibody

Binding Specificity: AA 100-280

Purification: Protein A Chromatography

Immunogen: A partial length recombinant CUEDC2 protein (amino acids 100-280) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 1-2 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for CUEDC2

Target: CUEDC2 (CUE Domain Containing 2 (CUEDC2))

Alternative Name: CUEDC2

Background: CUE domain-containing protein 2 commonly known as CUEDC2 is a 32 kDa protein having CUE Domain. It is involved in ubiquitin and proteasome-mediated degradation of progesterone receptor and estrogen receptor. It interacts with PRB isoform of progesterone receptor (PR) and modulates estrogen receptor (ER)-alpha protein stability through the ubiquitin-proteasome pathway. High level expression of CUEDC2 found in breast cancer tissue compared to normal adjacent tissue. It is found that CUEDC2 has some role in regulating IKK dephosphorylation by recruiting PP1.

Molecular Weight: 30 kDa

Gene ID: 79004

UniProt: Q9H467