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CUEDC2 antibody (AA 100-280)
CUEDC2
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CUEDC2 Antibody
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Target
See all CUEDC2 Antibodies
CUEDC2
(CUE Domain Containing 2 (CUEDC2))
Binding Specificity
All epitopes for CUEDC2 antibodies
AA 100-280
Reactivity
All reactivities for CUEDC2 antibodies
Human
Host
All hosts for CUEDC2 antibodies
Rabbit
Clonality
All clonalities for CUEDC2 antibodies
Polyclonal
Conjugate
All conjugates for CUEDC2 antibodies
This CUEDC2 antibody is un-conjugated
Application
All applications for CUEDC2 antibodies
Western Blotting (WB)
Purification
Protein A Chromatography
Immunogen
A partial length recombinant CUEDC2 protein (amino acids 100-280) was used as the immunogen for this antibody.
Isotype
IgG
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Application Details
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Application Notes
WB: 1-2 μg/mL
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Target Details for CUEDC2
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Target
CUEDC2
(CUE Domain Containing 2 (CUEDC2))
Alternative Name
CUEDC2 (CUEDC2 Products )
Synonyms
cuedc2 antibody, MGC81368 antibody, C10orf66 antibody, bA18I14.5 antibody, 3010002G01Rik antibody, wu:fi42e02 antibody, zgc:92255 antibody, CUE domain containing 2 S homeolog antibody, CUE domain containing 2 antibody, CUE domain containing 2 L homeolog antibody, cuedc2.S antibody, CUEDC2 antibody, cuedc2.L antibody, cuedc2 antibody, Cuedc2 antibody
Background
CUE domain-containing protein 2 commonly known as CUEDC2 is a 32 kDa protein having CUE Domain. It is involved in ubiquitin and proteasome-mediated degradation of progesterone receptor and estrogen receptor. It interacts with PRB isoform of progesterone receptor (PR) and modulates estrogen receptor (ER)-alpha protein stability through the ubiquitin-proteasome pathway. High level expression of CUEDC2 found in breast cancer tissue compared to normal adjacent tissue. It is found that CUEDC2 has some role in regulating IKK dephosphorylation by recruiting PP1.
Molecular Weight
30 kDa
Gene ID
79004
UniProt
Q9H467
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