DDX3X antibody (AA 10-230)

Catalog No. ABIN5027138

The Mouse Monoclonal anti-DDX3X antibody (Clone ABM27H2) (ABIN5027138) specifically detects DDX3X in WB. The antibody is reactive with Human samples.

Quick Overview for DDX3X antibody (AA 10-230) (ABIN5027138)

Target: DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DDX3X antibody is un-conjugated

Application: Western Blotting (WB)

Clone: ABM27H2

Product Details anti-DDX3X Antibody

Binding Specificity: AA 10-230

Cross-Reactivity: Mouse (Murine)

Purification: Protein G Chromatography

Immunogen: A partial length recombinant DDX3 protein (amino acids 10-230) was used as the immunogen for this antibody.

Isotype: IgG2b kappa

Application Details

Application Notes: WB: 2-4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for DDX3X

Target: DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))

Alternative Name: DDX3

Background: DDX3 (DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked) is having a large family of ATP-dependent RNA helicases that involve in several steps of RNA metabolism. Main functions of DDX3 involve transcription, mRNA export and translation, regulation of apoptosis and hepatitis C virus (HCV) replication. DDX3 has two isoforms produced by alternative splicing. The cytoplasmic form is highly phosphorylated in the G1/S. DDX3 is primarily expressed in nucleus during G0 phase and in the cytoplasm during G1/S phase.

Molecular Weight: 73 kDa

Gene ID: 1654

UniProt: O00571

Pathways: Ribonucleoprotein Complex Subunit Organization, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Ribosome Assembly