Desmoglein 3 antibody (AA 328-526)
Quick Overview for Desmoglein 3 antibody (AA 328-526) (ABIN5027152)
Target
See all Desmoglein 3 (DSG3) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Binding Specificity
- AA 328-526
-
Purification
- Protein G Chromatography
-
Immunogen
- A partial length recombinant Desmoglein 3 protein (amino acids 328-526) was used as the immunogen for this antibody.
-
Isotype
- IgG2b kappa
-
-
anti-Desmoglein 3 (DSG3) (AA 55-159) antibody
DSG3 Reactivity: Human WB, IHC, ELISA, FACS Host: Mouse Monoclonal 6G2C11 unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 Reactivity: Human IHC, StM Host: Mouse Monoclonal DSG3-2840 unconjugated
anti-Desmoglein 3 (DSG3) (AA 858-999) antibodyDSG3 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 Reactivity: Human IHC Host: Mouse Monoclonal MSVA-543M unconjugated
anti-Desmoglein 3 (DSG3) (AA 70-615) antibodyDSG3 Reactivity: Human IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 50-75) antibodyDSG3 Reactivity: Mouse, Rat WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) antibodyDSG3 Reactivity: Human WB, IF Host: Rabbit Monoclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 Reactivity: Human WB, ELISA, Coat Host: Mouse Monoclonal DSG3-2796 unconjugated
anti-Desmoglein 3 (DSG3) antibodyDSG3 Reactivity: Human WB, IHC, IF, FACS, StM Host: Mouse Monoclonal 5G11 unconjugated
anti-Desmoglein 3 (DSG3) (AA 334-604) antibodyDSG3 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C5 unconjugated
-
-
Application Notes
- IHC: 1 μg/mL
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 0.5 mg/mL
-
Buffer
- PBS containing 0.05 % BSA, PH 7.4
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C/-20 °C
-
Storage Comment
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
-
-
- Desmoglein 3 (DSG3)
-
Alternative Name
- Desmoglein 3
-
Background
- DSG3 (Desmoglein 3) is a calcium-binding transmembrane glycoprotein component of desmosomes, conferring strong cell-cell adhesion. Desmosomes are button-like points of intercellular contact that allow the attachment of cytoskeletal elements to the plasma membrane at sites of cell-cell adhesion. DSG3 is expressed in basal and immediate suprabasal layers of skin. To maintain cell-cell adhesion DSG3 interacts with other desmosomal proteins, such as plakoglobin. Plakoglobin is closely related to Beta-catenin, which is a well-known downstream effector molecule in the canonical Wnt signaling pathway.DSG3 also promotes cancer cell growth and invasion through a plakoglobin-mediated signaling pathway.
-
Gene ID
- 1830
-
UniProt
- P32926
Target
-
