Desmoglein 3 antibody (AA 379-491)
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- Target See all Desmoglein 3 (DSG3) Antibodies
- Desmoglein 3 (DSG3)
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Binding Specificity
- AA 379-491
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Desmoglein 3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Coating (Coat)
- Specificity
- Recognizes a protein of 130 kDa, identified as Desmoglein-3 (DSG3). This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Research has shown that DSG3 has a very high sensitivity (80 % ) and specificity (100 %) in recognizing squamous cell carcinoma (SqCC). Therefore, DSG3 is considered a very important marker for lung SqCC and can be a useful ancillary marker to separate SqCC from other subtypes of lung cancer. Moreover, studies have shown that DSG3 expression in lung SqCC may indicate a poor prognosis.
- Purification
- Purified by Protein A/G
- Immunogen
- Recombinant fragment (around aa 379-491) human DSG3 protein (exact sequence is proprietary)
- Clone
- DSG3-2796
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product DSG3 Primary Antibody
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anti-Desmoglein 3 (DSG3) (AA 55-159) antibody
DSG3 Reactivity: Human WB, ELISA, IHC, FACS Host: Mouse Monoclonal 6G2C11 unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 Reactivity: Human IHC, StM Host: Mouse Monoclonal DSG3-2840 unconjugated
anti-Desmoglein 3 (DSG3) (AA 858-999) antibodyDSG3 Reactivity: Human WB, ELISA, IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 Reactivity: Human IHC Host: Mouse Monoclonal MSVA-543M unconjugated
anti-Desmoglein 3 (DSG3) (AA 70-615) antibodyDSG3 Reactivity: Human ELISA, IF, IHC Host: Rabbit Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 50-75) antibodyDSG3 Reactivity: Mouse, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) antibodyDSG3 Reactivity: Human WB, IF, IHC, FACS, StM Host: Mouse Monoclonal 5G11 unconjugated
anti-Desmoglein 3 (DSG3) (Extracellular Domain) antibodyDSG3 Reactivity: Human WB, IF, FACS, IHC (p) Host: Mouse Monoclonal 5G11 unconjugated
anti-Desmoglein 3 (DSG3) antibodyDSG3 Reactivity: Human WB, IF Host: Rabbit Monoclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 334-604) antibodyDSG3 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C8 unconjugated
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- Application Notes
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Positive Control: A431 cells. Skin or Lung Squamous Cell Carcinoma (SCC).
Known Application: ELISA (For coating, order Ab without BSA), Western Blot (1-2 μg/mL)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Expiry Date
- 24 months
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- Target
- Desmoglein 3 (DSG3)
- Alternative Name
- DSG3 (DSG3 Products)
- Synonyms
- DSG3 antibody, CDHF6 antibody, PVA antibody, bal antibody, balding antibody, desmoglein 3 antibody, DSG3 antibody, Dsg3 antibody
- Molecular Weight
- 130kDa
- Gene ID
- 1830
- UniProt
- P32926
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