DMAP1
Reactivity: Human
WB
Host: Rabbit
Monoclonal
unconjugated
Application Notes
WB: 2-4 μg/mL
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Target
DMAP1
(DNA Methyltransferase 1-Associated Protein 1 (DMAP1))
Alternative Name
DMAP1
Background
DNA methyltransferase 1-associated protein 1 is an enzyme that in humans is encoded by the DMAP1 gene and consisting of 433 aminoacids. It is involved in transcription repression and activation. DMAP1 interacts with HDAC2 which provides a mechanism for histone deacetylation in heterochromatin following replication of DNA at late dismissal origins. DMAP1 can also repress transcription independently of histone deacetylase activity. It participates in the nuclear localization of URI1 and increases its transcriptional co-repressor activity. It is expressed in adipose tissue, adrenal gland, amniotic fluid, cerebellar cortex, hippocampus, liver, etc.