IL1RL2 antibody (AA 1-203)

Catalog No. ABIN5027302

The Mouse Monoclonal anti-IL1RL2 antibody is suitable to detect IL1RL2 in samples from Human. It has been validated for WB.

Quick Overview for IL1RL2 antibody (AA 1-203) (ABIN5027302)

Target: IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL1RL2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: ABM47A2

Product Details anti-IL1RL2 Antibody

Binding Specificity: AA 1-203

Purification: Protein G Chromatography

Immunogen: A partial length recombinant IL-36R protein (amino acids 1-203) was used as the immunogen for this antibody.

Isotype: IgG2b

Application Details

Application Notes: WB: 2-4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for IL1RL2

Target: IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

Alternative Name: IL-36R

Background: IL-36R is a member of the IL-1 receptor family that has been associated with various inflammation-associated diseases. Ligands binding to IL-36R subsequently recruit the IL-1RAcP (IL-1 Receptor Accessory Protein) forming a heterodimeric signaling complex. The latter is also used by IL-1Alpha and IL-1Beta. IL-36R is expressed by different immune cells, including Dendritic Cells, microglia and other myeloid cells. IL-36 stimulation of DC leads to the production of several cytokines by DC, including TNF-a, IL-1, IL-12, and IL-23. This interaction also enhances the expression of MHC class 2 and co-stimulatory molecules.

Molecular Weight: 69 kDa

Gene ID: 8808

UniProt: Q9HB29