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IPO7 antibody (AA 1-322)
IPO7
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IPO7 Antibody
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Target
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IPO7
(Importin 7 (IPO7))
Binding Specificity
All epitopes for IPO7 antibodies
AA 1-322
Reactivity
All reactivities for IPO7 antibodies
Human
Host
All hosts for IPO7 antibodies
Rabbit
Clonality
All clonalities for IPO7 antibodies
Polyclonal
Conjugate
All conjugates for IPO7 antibodies
This IPO7 antibody is un-conjugated
Application
All applications for IPO7 antibodies
Western Blotting (WB)
Purification
Protein A Chromatography
Immunogen
A partial length recombinant Importin 7 protein (amino acids 1-322) was used as the immunogen for this antibody.
Isotype
IgG
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Application Details
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Application Notes
WB: 1-2 μg/mL
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Target Details for IPO7
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Target
IPO7
(Importin 7 (IPO7))
Alternative Name
Importin 7 (IPO7 Products )
Synonyms
fb33d09 antibody, wu:fb33d09 antibody, zgc:66425 antibody, zgc:76878 antibody, imp7 antibody, ranbp7 antibody, Imp7 antibody, RANBP7 antibody, A330055O14Rik antibody, C330016G14 antibody, Ranbp7 antibody, importin 7 antibody, importin 7 S homeolog antibody, importin-7 antibody, karyopherin antibody, ipo7 antibody, ipo7.S antibody, IPO7 antibody, CpipJ_CPIJ002096 antibody, PTRG_08544 antibody, SJAG_03693 antibody, NAEGRDRAFT_71372 antibody, VDBG_01971 antibody, MGYG_08162 antibody, Tsp_01943 antibody, Tsp_01946 antibody, Ipo7 antibody
Background
Importin 7 (IPO7) is a soluble nuclear transport factor that is required for efficient import. It mediates transport of hTERT into the nucleus. Efficient transport also requires the cytoplasmic nucleoporin Nup358, which was previously implicated in nuclear import of a subset of proteins. Importin 7 plays an important role in nuclear protein import either by acting as autonomous nuclear transport receptor, or as an adapter like protein in association with the importin-beta subunit KPNB1. It serves itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism.
Molecular Weight
115 kDa
Gene ID
10527
UniProt
O95373
Pathways
Protein targeting to Nucleus
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