Importin 9 antibody (AA 840-1041)
Quick Overview for Importin 9 antibody (AA 840-1041) (ABIN5027316)
Target
See all Importin 9 (IPO9) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 840-1041
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Purification
- Protein A Chromatography
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Immunogen
- A partial length recombinant Importin-9 protein (amino acids 840-1,041) was used as the immunogen for this antibody.
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Isotype
- IgG
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Application Notes
- WB: 0.25-1.0 μg/mL, IHC: 5 μg/mL
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.05 % BSA, PH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Importin 9 (IPO9)
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Alternative Name
- Importin-9 (Ran-binding protein 9)
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Background
- Importin-9 (IPO9) is a molecular transporter and chaperone that belongs to the super-family of karyopherins. It binds primarily to stem-loop structure 1 in IFN-epsilon5'UTR, and negatively impacts mRNA expression. Importins, including Importin-9, are known for their ability to mediate active transport through nuclear pore complexes and effectively suppress the aggregation of their basic import cargoes in polyanionic environments. Importins exert their functions through protein-protein interactions, they recognize nuclear localization signals and prevent protein aggregation by shielding basic patches such as those found in a variety of ribosomal proteins.
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Molecular Weight
- 115 kDa
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Gene ID
- 55705
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UniProt
- Q96P70
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Pathways
- Protein targeting to Nucleus
Target
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