Importin 9 antibody (AA 1-388)

Catalog No. ABIN6242408

Product Details anti-Importin 9 Antibody

Target: Importin 9 (IPO9)

Binding Specificity: AA 1-388

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Importin 9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This RANBP9 antibody is generated from a mouse immunized with a recombinant protein between 1-388 amino acids from the human RANBP9.

Clone: 1815CT202-22-8-37

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 1:2000-1:4000. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for Importin 9

Target: Importin 9 (IPO9)

Alternative Name: RANBP9 (IPO9 Products)

Synonyms: Imp9 antibody, 0710008K06Rik antibody, AI845704 antibody, C78347 antibody, Ranbp9 antibody, mKIAA1192 antibody, zgc:66429 antibody, wu:fc23d12 antibody, MGC81741 antibody, IPO9 antibody, DDBDRAFT_0205722 antibody, DDBDRAFT_0229883 antibody, DDB_0205722 antibody, DDB_0229883 antibody, RGD1561940 antibody, RanBPM antibody, RanBP9 antibody, bpm-l antibody, bpm90 antibody, ranbp9 antibody, ranbp9-a antibody, ranbp9-b antibody, ranbp9b antibody, cb457 antibody, zgc:158650 antibody, importin 9 antibody, importin 9 L homeolog antibody, RAN binding protein 9 antibody, RAN binding protein 9 L homeolog antibody, IPO9 antibody, Ipo9 antibody, ipo9 antibody, ipo9.L antibody, cnrP antibody, Ranbp9 antibody, ranbp9.L antibody, RANBP9 antibody, ranbp9 antibody

Background: May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA (By similarity).

Molecular Weight: 77847

UniProt: Q96S59

Pathways: Protein targeting to Nucleus