Inhibin alpha antibody (AA 196-366)

Catalog No. ABIN5027320

The Mouse Monoclonal anti-Inhibin alpha antibody is suitable to detect Inhibin alpha in samples from Human. It has been validated for WB and IHC.

Quick Overview for Inhibin alpha antibody (AA 196-366) (ABIN5027320)

Target: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Inhibin alpha antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: ABM44F5

Product Details anti-Inhibin alpha Antibody

Binding Specificity: AA 196-366

Purification: Protein G Chromatography

Immunogen: A partial length recombinant Inhibin alpha protein (amino acids 196-366) was used as the immunogen for this antibody.

Isotype: IgG2b kappa

Application Details

Application Notes: WB: 0.5-1, IHC-5-10 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for Inhibin alpha

Target: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Alternative Name: Inhibin alpha

Background: Inhibin alpha (INHA) are dimeric glycoproteins that are structurally and functionally related to transforming growth factor-beta and are composed of 1 Alpha-subunit and 1 of 2 beta-subunits (betaA or betaB). Inhibin, first identified as a hormone regulating pituitary FSH secretion, later recognized to act as a tumor suppressor in the gonad and adrenal glands. INHA are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins play important roles in normal gonadal function, including regulation of proliferation, differentiation, and steroidogenesis of Leydig and Sertoli cells via paracrine and autocrine processes.

Molecular Weight: 35 kDa

Gene ID: 3623

UniProt: P05111

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion