KLF10/TIEG1 antibody (AA 11-221)

Catalog No. ABIN5027328

Product Details anti-KLF10/TIEG1 Antibody

Target: KLF10/TIEG1 (KLF10) (Kruppel-Like Factor 10 (KLF10))

Binding Specificity: AA 11-221

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF10/TIEG1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogen: A partial length recombinant KLF10 protein (amino acids 11-221) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 1-2 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for KLF10/TIEG1

Target: KLF10/TIEG1 (KLF10) (Kruppel-Like Factor 10 (KLF10))

Alternative Name: KLF10 (KLF10 Products)

Synonyms: EGR-alpha antibody, EGRA antibody, TIEG antibody, TIEG1 antibody, AI115143 antibody, EGR[a] antibody, Egral antibody, Gdnfif antibody, Tieg antibody, Tieg1 antibody, mGIF antibody, KLF10 antibody, DKFZp459O142 antibody, fc23d01 antibody, wu:fc23d01 antibody, klf10 antibody, Kruppel like factor 10 antibody, Kruppel-like factor 10 antibody, Kruppel-like factor 10 S homeolog antibody, KLF10 antibody, Klf10 antibody, klf10 antibody, klf10.S antibody

Background: Kruppel-like factor 10 (KLF10 ) is a member of the Kruppel-like family of transcription factors, which are known to be involved in anti-proliferative and apoptotic inducing functions following TGF-beta induction. KLF10 plays an important role in the repression of proliferative and hypertrophic pathways, possibly through the actions of PTTG1 (pituitary tumor-transforming gene 1). KLF10 is found to be predominantly expressed in various tissues and its expression is regulated by cytokines and growth factors. Over-expression of KLF10 has been found to induce apoptosis in pancreatic cancer cells. In addition, KLF10 induces apoptosis via a mechanism which involves the formation of reactive oxygen species.

Molecular Weight: 46 kDa

Gene ID: 7071

UniProt: Q13118

Pathways: Stem Cell Maintenance