OTX2 antibody (AA 1-204)

Catalog No. ABIN5027412

This Rabbit Polyclonal antibody specifically detects OTX2 in WB. It exhibits reactivity toward Human.

Quick Overview for OTX2 antibody (AA 1-204) (ABIN5027412)

Target: OTX2 (Orthodenticle Homeobox 2 (OTX2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OTX2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OTX2 Antibody

Binding Specificity: AA 1-204

Purification: Protein A Chromatography

Immunogen: A partial length recombinant Otx2 protein (amino acids 1-204) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 2-4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for OTX2

Target: OTX2 (Orthodenticle Homeobox 2 (OTX2))

Alternative Name: Otx2

Background: Otx2 encodes a transcription factor that plays a critical role in craniofacial development and anterior brain morphogenesis. Otx2 homologs in model organisms are expressed in a complex spatial, temporal, and gradient-specific manner that is required for correct antero-posterior patterning and craniofacial development. Otx2 mutations are associated with severe ocular phenotypes and central nervous system abnormalities such as seizures, short stature and developmental delay, CPHD (Combined Pituitary Hormone Deficiency), structural abnormalities of the pituitary gland and early onset retinal dystrophy.

Molecular Weight: 32 kDa

Gene ID: 5015

UniProt: P32243

Pathways: Dopaminergic Neurogenesis