POU3F2 antibody (AA 220-421)

Catalog No. ABIN5027442

Product Details anti-POU3F2 Antibody

Target: POU3F2 (POU Class 3 Homeobox 2 (POU3F2))

Binding Specificity: AA 220-421

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POU3F2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogen: A partial length recombinant POU3F2 protein (amino acids 220-421) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 1-2 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for POU3F2

Target: POU3F2 (POU Class 3 Homeobox 2 (POU3F2))

Alternative Name: POU3F2 (POU3F2 Products)

Synonyms: BRN2 antibody, N-Oct3 antibody, OCT7 antibody, OTF-7 antibody, OTF7 antibody, POUF3 antibody, brn-2 antibody, oct-7 antibody, XlPOU3 antibody, pou3f2 antibody, pou3f2-A antibody, pou3f4 antibody, 9430075J19Rik antibody, A230098E07Rik antibody, Brn-2 antibody, Brn2 antibody, Otf7 antibody, XLPOU3b antibody, pou47 antibody, zp47 antibody, zp47pou antibody, brn-1.2 antibody, brn1.2 antibody, id:ibd5088 antibody, POU class 3 homeobox 2 antibody, POU class 3 homeobox 2 L homeolog antibody, POU domain, class 3, transcription factor 2 antibody, POU class 3 homeobox 2 S homeolog antibody, POU class 3 homeobox 2b antibody, POU class 3 homeobox 2a antibody, POU3F2 antibody, pou3f2.L antibody, Pou3f2 antibody, pou3f2.S antibody, pou3f2b antibody, pou3f2a antibody

Background: POU3F2 is a developmental neural cell-specific POU domain transcription factor and is crucial for cell lineage determination. In melanoma lesions, cells expressing high levels of POU3F2 show enhanced invasive and metastatic capacity that can in part be explained by repression of MITF (Micropthalmia-associated Transcription Factor) expression via POU3F2 binding to its promoter. POU3F2 is expressed exclusively in the central nervous system, more specifically in postmitotic neurons and glia.

Molecular Weight: 27 kDa

Gene ID: 5454

UniProt: P20265