CD68 antibody (AA 80-280)

Catalog No. ABIN5027460

This Mouse Monoclonal antibody specifically detects CD68 in FACS and WB. It exhibits reactivity toward Human.

Quick Overview for CD68 antibody (AA 80-280) (ABIN5027460)

Target: CD68 (CD68 Molecule (CD68))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD68 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB)

Clone: ABM53F5

Product Details anti-CD68 Antibody

Binding Specificity: AA 80-280

Purification: Protein G Chromatography

Immunogen: A partial length recombinant protein (a.a 80-280) of CD28 was used as the immunogen for this antibody.

Isotype: IgG2b kappa

Application Details

Application Notes: FACS: 0.5-1 μg/10^6 cells, WB: 2-4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for CD68

Target: CD68 (CD68 Molecule (CD68))

Alternative Name: CD68

Background: CD68 is a transmembrane glycoprotein which acts as a commercialized marker for human monocytes and macrophages. Its expression is thought to be regulated by a macrophage-specific promoter. However, several immunohistochemical studies have indicated that CD68 antibodies also react with other haematopoietic and non-haematopoietic cell types. It also can stain myeloid cells, dendritic cells, fibroblasts, Langerhans cells and others. In human monocytes, which produce high levels of CD68 mRNA, the gene is characterized by intramolecular ligations between the promoter and the 3'intervening region. CD68 is also used as a pan-macrophage marker for TAM (Tumor-Associated Macrophages) which always involve in carcinogenesis.

Molecular Weight: 42 kDa

Gene ID: 968

UniProt: P34810