S1PR3 antibody (AA 80-350)

Catalog No. ABIN5027517

This Rabbit Polyclonal antibody specifically detects S1PR3 in WB. It exhibits reactivity toward Human.

Quick Overview for S1PR3 antibody (AA 80-350) (ABIN5027517)

Target: S1PR3 (Sphingosine-1-Phosphate Receptor 3 (S1PR3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S1PR3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-S1PR3 Antibody

Binding Specificity: AA 80-350

Purification: Protein A Chromatography

Immunogen: A partial length recombinant S1P3 receptor, Edg-3 protein (amino acids 80-350) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 2-4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for S1PR3

Target: S1PR3 (Sphingosine-1-Phosphate Receptor 3 (S1PR3))

Alternative Name: S1P3 receptor, Edg-3

Background: S1PR3 (sphingosine-1phosphate receptor3) is a vascular barrier regulatory member of the S1P family of receptors (S1PR15) and a critical signaling molecule mediating cell proliferation, adhesion, angiogenesis, and vascular permeability. In a nitrated form protein in plasma it is found as a biomarker in patients with ALI (acute lung injury). S1PR3 plays an important role in promoting pulmonary inflammation, disrupting cell-cell junctions, and increasing lung permeability and alveolar flooding during inflammation.

Molecular Weight: 40 kDa

Gene ID: 1903

UniProt: Q99500