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S1PR3 antibody (AA 80-350)
S1PR3
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-S1PR3 Antibody
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Target
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S1PR3
(Sphingosine-1-Phosphate Receptor 3 (S1PR3))
Binding Specificity
All epitopes for S1PR3 antibodies
AA 80-350
Reactivity
All reactivities for S1PR3 antibodies
Human
Host
All hosts for S1PR3 antibodies
Rabbit
Clonality
All clonalities for S1PR3 antibodies
Polyclonal
Conjugate
All conjugates for S1PR3 antibodies
This S1PR3 antibody is un-conjugated
Application
All applications for S1PR3 antibodies
Western Blotting (WB)
Purification
Protein A Chromatography
Immunogen
A partial length recombinant S1P3 receptor, Edg-3 protein (amino acids 80-350) was used as the immunogen for this antibody.
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB: 2-4 μg/mL
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Target Details for S1PR3
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Target
S1PR3
(Sphingosine-1-Phosphate Receptor 3 (S1PR3))
Alternative Name
S1P3 receptor, Edg-3 (S1PR3 Products )
Synonyms
s1pr3 antibody, si:dkeyp-31e2.1 antibody, EDG-3 antibody, EDG3 antibody, LPB3 antibody, S1P3 antibody, AI132464 antibody, Edg3 antibody, Lpb3 antibody, S1p3 antibody, sphingosine-1-phosphate receptor 3 antibody, sphingosine-1-phosphate receptor 3a antibody, S1PR3 antibody, s1pr3a antibody, S1pr3 antibody
Background
S1PR3 (sphingosine-1phosphate receptor3) is a vascular barrier regulatory member of the S1P family of receptors (S1PR15) and a critical signaling molecule mediating cell proliferation, adhesion, angiogenesis, and vascular permeability. In a nitrated form protein in plasma it is found as a biomarker in patients with ALI (acute lung injury). S1PR3 plays an important role in promoting pulmonary inflammation, disrupting cell-cell junctions, and increasing lung permeability and alveolar flooding during inflammation.
Molecular Weight
40 kDa
Gene ID
1903
UniProt
Q99500
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