S1PR1 antibody (AA 1-320)

Catalog No. ABIN5027519

The Rabbit Polyclonal anti-S1PR1 antibody (ABIN5027519) specifically detects S1PR1 in WB. The antibody is reactive with Human samples.

Quick Overview for S1PR1 antibody (AA 1-320) (ABIN5027519)

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S1PR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-S1PR1 Antibody

Binding Specificity: AA 1-320

Purification: Protein A Chromatography

Immunogen: A partial length recombinant S1PR1 protein (amino acids 1-320) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB:4-6 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for S1PR1

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Alternative Name: S1PR1

Background: Sphingosine-1-phosphate receptor 1 (S1P receptor 1 or S1P1), also known as endothelial differentiation gene 1 (EDG1) is a protein that in humans is encoded by the S1PR1 gene. S1PR1 plays an important role in cell migration reorganizing the actin cytoskeleton and by the formation of lamellipodia in response to the activity of sphingosine kinase SPHK1. Diseases associated with S1PR1 include follicular thyroid carcinoma and multiple sclerosis. It is mainly expressed on endothelial cells, vascular smooth muscle cells (low), fibroblasts, melanocytes and cells of epithelioid origin.

Molecular Weight: 40 kDa

Gene ID: 1901

UniProt: P21453

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2