SOX11 antibody (AA 23-236)

Catalog No. ABIN5027535

This Mouse Monoclonal antibody specifically detects SOX11 in WB. It exhibits reactivity toward Human.

Quick Overview for SOX11 antibody (AA 23-236) (ABIN5027535)

Target: SOX11 (SRY (Sex Determining Region Y)-Box 11 (SOX11))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SOX11 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: ABM45D9

Product Details anti-SOX11 Antibody

Binding Specificity: AA 23-236

Purification: Protein G Chromatography

Immunogen: A partial length recombinant Sox11 protein (amino acids 23-236) was used as the immunogen for this antibody.

Isotype: IgG2b kappa

Application Details

Application Notes: WB: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for SOX11

Target: SOX11 (SRY (Sex Determining Region Y)-Box 11 (SOX11))

Alternative Name: SOX11

Background: SOX11 (Sex determining region Y-box 11), located on chromosome 2p25, belong to the family of genes SOXC. It is a transcript factor involved in the embryonic neurogenesis and tissue remodeling, also participating in the control of cell proliferation. It is involved in gastrulation and in malignant diseases. It is expressed in foetal and neoplastic brain tissue, including gliomas (23619925). SOX11 is overexpressed in several solid tumors and in the vast majority of aggressive mantle cell lymphomas (MCLs). Diseases associated with SOX11 include mental retardation, autosomal dominant, 27 and coffin-siris syndrome.

Molecular Weight: 45 kDa

Gene ID: 6664

UniProt: P35716

Pathways: Tube Formation