IFRD1 antibody (AA 1-300)

Catalog No. ABIN5027565

Product Details anti-IFRD1 Antibody

Target: IFRD1 (Interferon Related Developmental Regulator 1 (IFRD1))

Binding Specificity: AA 1-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFRD1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogen: A partial length recombinant Tis7 protein (amino acids 1-300) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 2-4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for IFRD1

Target: IFRD1 (Interferon Related Developmental Regulator 1 (IFRD1))

Alternative Name: Tis7 (IFRD1 Products)

Synonyms: im:7067566 antibody, si:dkey-192l17.2 antibody, wu:fi35f04 antibody, wu:fj67a06 antibody, zgc:154080 antibody, IFR1 antibody, PC4 antibody, TIS7 antibody, Ifnl antibody, Tis7 antibody, Pc4 antibody, interferon-related developmental regulator 1 antibody, interferon related developmental regulator 1 L homeolog antibody, interferon related developmental regulator 1 antibody, ifrd1 antibody, ifrd1.L antibody, IFRD1 antibody, Ifrd1 antibody

Background: Tis7/IFRD1 (interferon-related developmental regulator 1) is expressed by neutrophils as a key modifier gene in cystic fibrosis (CF) lung disease. It functions as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. In skeletal muscle cells, Tis7 is known to function as a coactivator of MyoD by promoting the transcriptional activity of myocyte enhancer factor 2C (MEF2C). Mutations in Tis7 are associated with sensory/motor neuropathy with ataxia.

Molecular Weight: 55 kDa

Gene ID: 3475

UniProt: O00458