USP7 antibody (AA 932-1100)
Quick Overview for USP7 antibody (AA 932-1100) (ABIN5027625)
Target
See all USP7 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 932-1100
-
Purification
- Protein A Chromatography
-
Immunogen
- A partial length recombinant USP7 protein (amino acids 932-1100) was used as the immunogen for this antibody.
-
Isotype
- IgG
-
-
-
-
Application Notes
- WB: 2-4 μg/mL
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 0.5 mg/mL
-
Buffer
- PBS containing 0.05 % BSA, PH 7.4
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C/-20 °C
-
Storage Comment
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
-
-
- USP7 (Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))
-
Alternative Name
- USP7
-
Background
- USP7 (ubiquitin specific peptidase 7) is a deubiquitinating enzyme that prevents protein degradation by removing poly-ubiquitin chains from its substrates. It regulates stability of a number of human transcription factors and tumor suppressors and plays a critical role in the development of several types of cancer, including prostate and small cell lung cancer.USP7 regulates Pol-eta (DNA polymerase eta) stability through both indirect and direct mechanisms. It regulates the stability of the DNA maintenance methyltransferase. Diseases associated with USP7 include UV-sensitive syndrome.
-
Molecular Weight
- 120 kDa
-
Gene ID
- 7874
-
UniProt
- Q93009
Target
-