RSAD2 antibody (AA 100-330)

Catalog No. ABIN5027637

Product Details anti-RSAD2 Antibody

Target: RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))

Binding Specificity: AA 100-330

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RSAD2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogen: A partial length recombinant Viperin protein (amino acids 100-330) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 3-5 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for RSAD2

Target: RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))

Alternative Name: Viperin (RSAD2 Products)

Synonyms: CIG6 antibody, RSAD2 antibody, 2510004L01Rik antibody, cig33 antibody, cig5 antibody, vig1 antibody, Vig1 antibody, Best5 antibody, si:ch211-276e8.2 antibody, zgc:112342 antibody, viperin antibody, rsad2 antibody, radical S-adenosyl methionine domain containing 2 antibody, viperin antibody, RSAD2 antibody, Rsad2 antibody, rsad2 antibody, vig1 antibody

Background: Radical S-adenosyl methionine domain-containing protein 2 is commonly known as Viperin consisting of 43 kDa protein. which is a interferon inducible viral protein. Viperin expression is induced by IFN, IFNb, IFNg, human cytomegalovirus (HCMV) envelope protein, glycoprotein B (gB), etc. Viperin interaction with the viral protein vMIA results in viperin relocalization from the endoplasmic reticulum to the mitochondria. It interacts with the mitochondrial trifunctional protein which mediates beta-oxidation of fatty acids to generate ATP. Viperin promotes TLR7 and TLR9-dependent production of IFN-beta and also plays an important role in CD4+ T-cell activation and differentiation. Viperin is highly expressed in mouse and human brain.

Molecular Weight: 40 kDa

Gene ID: 91543

UniProt: Q8WXG1

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response