RSAD2 antibody (AA 100-330)
Quick Overview for RSAD2 antibody (AA 100-330) (ABIN5027637)
Target
See all RSAD2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 100-330
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Purification
- Protein A Chromatography
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Immunogen
- A partial length recombinant Viperin protein (amino acids 100-330) was used as the immunogen for this antibody.
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Isotype
- IgG
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Application Notes
- WB: 3-5 μg/mL
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.05 % BSA, PH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))
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Alternative Name
- Viperin
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Background
- Radical S-adenosyl methionine domain-containing protein 2 is commonly known as Viperin consisting of 43 kDa protein. which is a interferon inducible viral protein. Viperin expression is induced by IFN, IFNb, IFNg, human cytomegalovirus (HCMV) envelope protein, glycoprotein B (gB), etc. Viperin interaction with the viral protein vMIA results in viperin relocalization from the endoplasmic reticulum to the mitochondria. It interacts with the mitochondrial trifunctional protein which mediates beta-oxidation of fatty acids to generate ATP. Viperin promotes TLR7 and TLR9-dependent production of IFN-beta and also plays an important role in CD4+ T-cell activation and differentiation. Viperin is highly expressed in mouse and human brain.
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Molecular Weight
- 40 kDa
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Gene ID
- 91543
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UniProt
- Q8WXG1
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Target
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