Aryl Hydrocarbon Receptor antibody (AA 721-820)

Catalog No. ABIN513203

The Mouse Monoclonal anti-Aryl Hydrocarbon Receptor antibody has been validated for WB, ELISA, IF, IP and RNAi. It is suitable to detect Aryl Hydrocarbon Receptor in samples from Human. There are 4+ publications available.

Quick Overview for Aryl Hydrocarbon Receptor antibody (AA 721-820) (ABIN513203)

Target: Aryl Hydrocarbon Receptor (AHR)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Aryl Hydrocarbon Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), RNA Interference (RNAi)

Clone: 3B12

Product Details anti-Aryl Hydrocarbon Receptor Antibody

Binding Specificity: AA 721-820

Purpose: Mouse monoclonal antibody raised against a partial recombinant AHR.

Sequence: MGSFEPSPYP TTSSLEDFVT CLQLPENQKH GLNPQSAIIT PQTCYAGAVS MYQCQPEPQH THVGQMQYNP VLPGQQAFLN KFQNGVLNET YPAELNNINN

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: AHR (NP_001612, 721 a.a. ~ 820 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Aryl Hydrocarbon Receptor antibody (ABIN513203)

Vogel, Khan, Leung, Gershwin, Chang, Wu, Haarmann-Stemmann, Hoffmann, Denison: "Cross-talk between aryl hydrocarbon receptor and the inflammatory response: a role for nuclear factor-?B." in: The Journal of biological chemistry, Vol. 289, Issue 3, pp. 1866-75, (2014) (PubMed).

Kalthoff, Winkler, Freiberg, Manns, Strassburg et al.: "Gender matters: estrogen receptor alpha (ER?) and histone deacetylase (HDAC) 1 and 2 control the gender-specific transcriptional regulation of human uridine diphosphate glucuronosyltransferases genes ..." in: Journal of hepatology, Vol. 59, Issue 4, pp. 797-804, (2013) (PubMed).

Vlachos, Schulte, Magiatis, Adema, Gaitanis: "Malassezia-derived indoles activate the aryl hydrocarbon receptor and inhibit Toll-like receptor-induced maturation in monocyte-derived dendritic cells." in: The British journal of dermatology, Vol. 167, Issue 3, pp. 496-505, (2012) (PubMed).

Schults, Timmermans, Godschalk, Theys, Wouters, van Schooten, Chiu: "Diminished carcinogen detoxification is a novel mechanism for hypoxia-inducible factor 1-mediated genetic instability." in: The Journal of biological chemistry, Vol. 285, Issue 19, pp. 14558-64, (2010) (PubMed).

Target Details for Aryl Hydrocarbon Receptor

Target: Aryl Hydrocarbon Receptor (AHR)

Alternative Name: AHR

Background: Full Gene Name: aryl hydrocarbon receptor
Synonyms: bHLHe76

Gene ID: 196

NCBI Accession: NM_001621

Pathways: Regulation of Cell Size