FAS antibody (AA 20-119)

Catalog No. ABIN513436

This Mouse Monoclonal antibody specifically detects FAS in WB and ELISA. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for FAS antibody (AA 20-119) (ABIN513436)

Target: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FAS antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 1D6

Product Details anti-FAS Antibody

Binding Specificity: AA 20-119

Purpose: Mouse monoclonal antibody raised against a partial recombinant FAS.

Sequence: SKSVNAQVTD INSKGLELRK TVTTVETQNL EGLHHDGQFC HKPCPPGERK ARDCTVNGDE PDCVPCQEGK EYTDKAHFSS KCRRCRLCDE GHGLEVEINC

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: FAS (NP_000034, 20 a.a. ~ 119 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-FAS antibody (ABIN513436)

Matsuda, Yamamoto, Takano, Kageyama, Kurobe, Yoshihara, Takano, Hattori: "Silencing of fas-associated death domain protects mice from septic lung inflammation and apoptosis." in: American journal of respiratory and critical care medicine, Vol. 179, Issue 9, pp. 806-15, (2009) (PubMed).

Matsuda, Teramae, Yamamoto, Takano, Takano, Hattori: "Increased death receptor pathway of apoptotic signaling in septic mouse aorta: effect of systemic delivery of FADD siRNA." in: American journal of physiology. Heart and circulatory physiology, Vol. 298, Issue 1, pp. H92-101, (2009) (PubMed).

Target Details for FAS

Target: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Alternative Name: FAS

Background: Full Gene Name: Fas (TNF receptor superfamily, member 6)
Synonyms: ALPS1A,APO-1,APT1,CD95,FAS1,FASTM,TNFRSF6

Gene ID: 355

NCBI Accession: NM_000043

Pathways: p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity