Caspase 3 antibody (AA 1-277)

Catalog No. ABIN514020

This anti-Caspase 3 antibody is a Rabbit Polyclonal antibody detecting Caspase 3 in WB, IF and PLA. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for Caspase 3 antibody (AA 1-277) (ABIN514020)

Target: Caspase 3 (CASP3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Proximity Ligation Assay (PLA)

Product Details anti-Caspase 3 Antibody

Binding Specificity: AA 1-277

Purpose: Rabbit polyclonal antibody raised against a full-length human CASP3 protein.

Sequence: MENTENSVDS KSIKNLEPKI IHGSESMDSG ISLDNSYKMD YPEMGLCIII NNKNFHKSTG MTSRSGTDVD AANLRETFRN LKYEVRNKND LTREEIVELM RDVSKEDHSK RSSFVCVLLS HGEEGIIFGT NGPVDLKKIT NFFRGDRCRS LTGKPKLFII QACRGTELDC GIETDSGVDD DMACHKIPVE ADFLYAYSTA PGYYSWRNSK DGSWFIQSLC AMLKQYADKL EFMHILTRVN RKVATEFESF SFDATFHAKK QIPCIVSMLT KELYFYH

Cross-Reactivity: Human, Mouse

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: CASP3 (AAH16926.1, 1 a.a. ~ 277 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Caspase 3 antibody (ABIN514020)

Huang, Chuang, Hao, Talbot, Sen, Trink, Sidransky, Ratovitski: "Phospho-?Np63? is a key regulator of the cisplatin-induced microRNAome in cancer cells." in: Cell death and differentiation, Vol. 18, Issue 7, pp. 1220-30, (2011) (PubMed).

Target Details for Caspase 3

Target: Caspase 3 (CASP3)

Alternative Name: CASP3

Background: Full Gene Name: caspase 3, apoptosis-related cysteine peptidase
Synonyms: CPP32,CPP32B,SCA-1

Gene ID: 836

NCBI Accession: NM_004346

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation