RUNX1 antibody (AA 210-310)

Catalog No. ABIN514054

This Mouse Monoclonal antibody specifically detects RUNX1 in WB, ELISA, IF and IHC (p). It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for RUNX1 antibody (AA 210-310) (ABIN514054)

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RUNX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2C10

Product Details anti-RUNX1 Antibody

Binding Specificity: AA 210-310

Purpose: Mouse monoclonal antibody raised against a partial recombinant RUNX1.

Sequence: RVSPHHPAPT PNPRASLNHS TAFNPQPQSQ MQDTRQIQPS PPWSYDQSYQ YLGSIASPSV HPATPISPGR ASGMTTLSAE LSSRLSTAPD LTAFSDPRQF P

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: RUNX1 (NP_001001890.1, 210 a.a. ~ 310 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-RUNX1 antibody (ABIN514054)

Niu, Kondo, Nakazawa, Oishi, Kawasaki, Mochizuki, Yamane, Katoh: "Transcription factor Runx2 is a regulator of epithelial-mesenchymal transition and invasion in thyroid carcinomas." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 92, Issue 8, pp. 1181-90, (2012) (PubMed).

Hussein, Dralle, Theophile, Kreipe, Bock: "Megakaryocytic expression of miRNA 10a, 17-5p, 20a and 126 in Philadelphia chromosome-negative myeloproliferative neoplasm." in: Annals of hematology, Vol. 88, Issue 4, pp. 325-32, (2009) (PubMed).

Target Details for RUNX1

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Alternative Name: RUNX1

Background: Full Gene Name: runt-related transcription factor 1
Synonyms: AML1,AML1-EVI-1,AMLCR1,CBFA2,EVI-1,PEBP2aB

Gene ID: 861

NCBI Accession: NM_001001890