CBS antibody (AA 1-551)

Catalog No. ABIN514085

The Rabbit Polyclonal anti-CBS antibody has been validated for WB. It is suitable to detect CBS in samples from Human. There are 2+ publications available.

Quick Overview for CBS antibody (AA 1-551) (ABIN514085)

Target: CBS (Cystathionine-beta-Synthase (CBS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CBS Antibody

Binding Specificity: AA 1-551

Purpose: Rabbit polyclonal antibody raised against a full-length human CBS protein.

Sequence: MPSETPQAEV GPTGCPHRSG PHSAKGSLEK GSPEDKEAKE PLWIRPDAPS RCTWQLGRPA SESPHHHTAP AKSPKILPDI LKKIGDTPMV RINKIGKKFG LKCELLAKCE FFNAGGSVKD RISLRMIEDA ERDGTLKPGD TIIEPTSGNT GIGLALAAAV RGYRCIIVMP EKMSSEKVDV LRALGAEIVR TPTNARFDSP ESHVGVAWRL KNEIPNSHIL DQYRNASNPL AHYDTTADEI LQQCDGKLDM LVASVGTGGT ITGIARKLKE KCPGCRIIGV DPEGSILAEP EELNQTEQTT YEVEGIGYDF IPTVLDRTVV DKWFKSNDEE AFTFARMLIA QEGLLCGGSA GSTVAVAVKA AQELQEGQRC VVILPDSVRN YMTKFLSDRW MLQKGFLKEE DLTEKKPWWW HLRVQELGLS APLTVLPTIT CGHTIEILRE KGFDQAPVVD EAGVILGMVT LGNMLSSLLA GKVQPSDQVG KVIYKQFKQI RLTDTLGRLS HILEMDHFAL VVHEQIQYHS TGKSSQRQMV FGVVTAIDLL NFVAAQERDQ K

Cross-Reactivity: Human, Mouse

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: CBS (NP_000062.1, 1 a.a. ~ 551 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-CBS antibody (ABIN514085)

Asimakopoulou, Panopoulos, Chasapis, Coletta, Zhou, Cirino, Giannis, Szabo, Spyroulias, Papapetropoulos: "Selectivity of commonly used pharmacological inhibitors for cystathionine ? synthase (CBS) and cystathionine ? lyase (CSE)." in: British journal of pharmacology, Vol. 169, Issue 4, pp. 922-32, (2013) (PubMed).

Qi, Zhou, Xiao, Tao, Gu, Jiang, Xu: "Promoter demethylation of cystathionine-?-synthetase gene contributes to inflammatory pain in rats." in: Pain, Vol. 154, Issue 1, pp. 34-45, (2012) (PubMed).

Target Details for CBS

Target: CBS (Cystathionine-beta-Synthase (CBS))

Alternative Name: CBS

Background: Full Gene Name: cystathionine-beta-synthase
Synonyms: HIP4

Gene ID: 875

NCBI Accession: NM_000071